Seattle at San Francisco

San Francisco is ready to make another late run for its third straight win after defeating Dallas and Tampa Bay. The 49ers have covered four of five following an ATS loss, and Seattle has been 1-5 ATS in the past six meetings. The Seahawks have lost five of six with a 1-5 ATS record, including 26-20 in overtime to the Rams two weeks ago before their bye week. Seattle has gone UNDER three in a row, and Geno Smith threw three picks against the Rams, although he did have 363 passing yards and three TDs. San Francisco has won the past six meetings outright, and Seattle has lost seven of its past eight November games. Brock Purdy went 25-for-36 for 353 yards and two TDs with no interceptions against the Buccaneers, and the 49ers now have Christian McCaffrey back. San Francisco went UNDER for the third time in five games as the Bucs totaled only 215 yards of offense. Take the 49ers and the UNDER.