San Francisco at Washington

Undefeated San Francisco had a divisional showdown at the Rams last week and won 20-7. Now they have to travel on the road again, 3,000 miles to the East Coast in a tough situational spot. The 49ers are on a 4-10 spread run against the NFC, 5-11 ATS in October games, as well as 10-23 ATS on the road versus a team with a winning percentage below 25%. Washington comes off a win at Miami, rallying around interim coach Bill Callahan in his first game. And NFL underdogs of 3.5 to 10.5 points that are being outscored by 7+ points per game are 183-117 ATS after scoring 17 points or less in three straight games. Back Washington.