San Francisco at Chicago

San Francisco comes off a 19-13 loss to Arizona as the 49ers covered the number in a decent defensive showing, holding the Cardinals to just 2.4 yards per carry. Blaine Gabbert played reasonably well completing 25-of-36 for 318 yards. The Niners are averaging 295.5 yards of total offense this season while allowing 397.9. Chicago stunned Green Bay 17-13 on Thanksgiving Day as Jay Cutler compled 19-of-31 for 200 yards and a touchdown. Cutler has completed 63.2 percent of his passes for 2510 yards and 14 touchdowns and six interceptions. It was an emotional night both for the Bears who were seeking revenge for last year and also for the Packers who were celebrating Brett Favre's career. The 49ers are looking for their first road win of the season, but the Bears are just 1-4 at home. Gabbert has a 65.3 percent completion rate in three games with a total of four touchdown passes and three interceptions. The 49ers are 4-1 ATS after a loss and the Bears are 7-19-1 ATS their last 27 home games and 5-11 ATS in December. Also, the OVER is 24-8 in Bears' games after a win. Play the 49ers and the OVER.