Pittsburgh at Seattle

A long road trip for Pittsburgh. The offense has averaged just 13.8 points in its last five road contests. That included a 30-6 loss at Houston as a favorite and a 30-13 defeat at Indianapolis in their last road game. With QB Kenny Pickett injured, backup quarterback Mason Rudolph will make his second consecutive start. The defense is 21st in yards allowed and 22nd on third down (39.81%). Seattle has won five of its seven home games and would be in the playoffs if the season ended now. They've won three of four with QB Geno Smith (19 TDs, 8 INTs) throwing 5 touchdowns with just one pick. With Seattle winning six of its last nine overall, the wagering value is on the home team to win the game. Play Seattle on the moneyline.