Pittsburgh at San Francisco

Both teams went OVER last week with Pittsburgh losing 28-26 to Seattle and San Francisco blowing out the Bengals 41-17. The posted total is deflated in this matchup probably due to the absence of injured Ben Roethlisberger, but Mason Rudolph stepped in and completed 12-of-19 passes for 112 yards with two touchdowns and an interception.  The Steelers also got some production on the ground with 81 rushing yards after gaining only 32 in the season opener against New England. San Francisco breezed past Cincinnati as Jimmy Garoppolo tied his career-high with three TD passes and the 49ers racked up 572 total yards for their most in seven years. The Niners are averaging 36 points and the game went OVER by 12 points. Pittsburgh has gone OVER in 10 of its last 14 in Week 3 and the Niners have gone OVER in four straight in the third game of the season. Also, the 49ers are 7-1 OVER when following a win and 4-1 OVER in their last five September games. Play the OVER.