New York at San Francisco

A pair of talented defenses clash. New York was third in the NFL last season in yards allowed, 12th in points given up, 12th on third down (37.19%), and 11th in yards per rush allowed. The Jets have one of the NFL's best defensive fronts led by Quinnen Williams, who had a team-high 70 pressures in 2023. San Francisco was eighth in the league last year in yards allowed and third in points given up. The 49ers have All-Pros on defense in edge rusher Nick Bosa, linebacker Fred Warner, cornerback Charvarius Ward and safety Talanoa Hufanga. The UNDER is 5-1 when the 49ers play in September, when defenses are often ahead of the offense, plus 9-1 UNDER in Week 1. And NFL prime-time games are 70-42-1 UNDER the total over the last two seasons. Take New York/San Francisco UNDER the total.