Los Angeles at Indianapolis

This is the first road game for Los Angeles. The Rams got a 20-point win with new QB Matthew Stafford, though the final was a little misleading. It was 20-14 in the third quarter, and the new-look offense was stagnant at times, rushing for just 74 yards (3.2 yards per carry). The Rams were a .500 road team last season, losing three of their first five away from home. Indianapolis has plenty of depth, balance, and talent and is coming off of an 11-5 season. They were out of sync in Week 1 last year, too, losing at Jacksonville before winning three straight at home by scores of 28-11, 36-7, and 31-27. New QB Carson Wentz threw for 251 yards against Seattle while the ground game had 113 yards. Plus, NFL dogs that averaged 275+ yards passing the previous season are 29-5 ATS after a game where they allowed 7 or more passing yards per attempt. Play Indianapolis.