Los Angeles at Arizona

Los Angeles QB Matthew Stafford threw for 317 yards in the opener, an OT loss to Detroit. The offense had 387 yards. The Rams are on a 7-1 spread run against the NFC West. Arizona comes off a 34-28 loss at Buffalo. The offense had just 270 total yards along with a turnover as QB Kyler Murray was sacked four times and the defense let a 17-3 lead slip away. Murray hadn't played in 11 months while rehabbing. The Cardinals are 1-6 ATS as a favorite and the Rams swept the season series last year with ease, 26-9 and 37-14. Play Los Angeles.