Kansas City at Los Angeles

Everyone likes to come hard at the defending champs, and Kansas City plays its first road game. The Chiefs are sensational on offense, but this is not an elite defense. In the opener, they allowed 118 yards rushing (5.4 yards per carry) to Houston and let a 31-7 lead slip to 31-20 in the fourth quarter. NFL favorites off a home win are 31-66 ATS in September games, plus favorites off a home victory are 37-77 ATS in the first month of the season. They are a big road favorite in this divisional game. Los Angeles opens new SoFi Stadium, so the players will be sky-high against the champs. They also come off a road victory at Cincinnati. It helps to be able to put pressure on star QB Pat Mahomes, and the Chargers can with a talented young line anchored by Joey Bosa and Melvin Ingram III. These rivals played close games last season (24-17, 31-21). NFL dogs that averaged 360+ total yards the previous season are 24-6 ATS in divisional games. With the Chargers 50-29 ATS on turf, back the big home divisional dog. Play Los Angeles.