Indianapolis at St. Louis

This looks like a week 16 or 17 of the regular season line, with the Colts having already clinched a playoffs spot. The big deal here is that Peyton Manning is recovering from neck surgery to correct a bulging disc and will sit this one out. Nevertheless, the Colts aren't 7 points worse than anyone, as their defense is vastly under valued because the emphasis is always on Manning and the offense. The Rams will be under Josh McDaniels as an offensive coordinator and with limited prep time, I expect a young QB in a new system to have an erratic game one and thus, I look for the Colts to at the very least stay within the number here. Indianapolis gets the call.