Houston at New Orleans

New Orleans ended last season on a heartbreaking note with the non-call on pass interference against the Rams, but the Saints come back this year looking even stronger as they have added tight end Jared Cook, and they still have Michael Thomas, who led the league with 125 catches for 1,045 yards and nine touchdowns. Drew Brees completed 74.4 percent of his passes and threw 32 touchdown passes with only five interceptions. Cameron Jordan leads a defense that has been more than adequate for the last two seasons, and the secondary should be much improved and mainly intact from last year. Houston suffered a huge loss when Lamar Miller went down for the season after tearing his ACL in the preseason, and the Texans will depend largely on the skills of Deshaun Watson, who threw for more than 4,000 yards last season. Still, questions remain concerning the offensive line that was overhauled for the third straight season. The Texans are 3-7-1 ATS their last 11 road games and 3-10 ATS their last 13 Monday games. Houston lost four of its last five against NFC teams. Play the Saints.