Houston at Buffalo

Houston has a big game against the Colts on deck but has to head to Buffalo first. They are not a healthy team, with J.J. Watt missing multiple practices this week with a groin injury, plus wide receiver DeAndre Hopkins is battling a sore hamstring. The Texans are 6-15-1 ATS following a spread win. Buffalo is desperate for a win also and home from a three-game trip riding a two-game skid. They are on a 2-1-1 ATS run, winning at the NY Jets and playing well in close losses at the Pats and Chiefs. LeSean McCoy has been impressive in the second half of the season, going over 100 all-purpose yards in five straight games. The Bills are 7-2 ATS following a loss and 6-1 ATS after a spread loss. Houston plays its home games indoors but now has to head outdoors into the Buffalo cold, and when these teams meet the favorite is 4-1 ATS in their last five meetings. Take Buffalo.