Detroit at San Francisco

Oddly, this game means nothing for Detroit as their meeting next week with the Vikings will determine No. 1 seed in the NFC. The Lions are getting healthier on a defense that is fourth against the run, seventh in points allowed, and No. 1 on third down. San Francisco's offensive line has been depleted by injuries with their quarterbacks throwing 18 TDs and 12 interceptions. They're 25th in the red zone. The 49ers' defense is a strength behind pass rusher Nick Bosa along with one of the best secondaries in the NFL. They've allowed only 200 net passing yards once in the last two months. Monday Night teams coming off a road loss are on have come in on the UNDER 57% of the time over the past 18 years. With the 49ers on a 4-2 run UNDER the total at home, look for more defense than offense. Take Detroit/San Francisco UNDER the total.