Detroit at Indianapolis

Detroit is on a remarkable 41-14-1 ATS run, including 8-1 ATS in its past eight games, and the Lions have won eight straight outright after obliterating Jacksonville 52-8 on Sunday. It was the most significant winning margin in franchise history, and the Lions also set a team record with 644 yards of offense. Jared Goff completed 24 of 29 for 412 yards and four TDs, and Detroit rushed for 196 yards on 43 carries. The Lions are 8-0 ATS after winning by at least 14 points, 7-0 ATS after allowing fewer than 250 total yards, and 6-0 after yielding fewer than 150 yards passing. Detroit has won its past five road games and is 10-3 ATS in its past 13 November games. Indianapolis had lost three in a row before beating the hapless Jets 28-27 when Anthony Richardson ran for a 4-yard TD with 46 seconds left. The Colts are averaging only 19.5 points in their past six games; four have gone UNDER. Its dominant offensive showings have overlooked Detroit's defense, but the Lions have allowed just 15.8 points per game in their past six. The Colts have stayed UNDER five of six versus NFC teams. Take the Lions and the UNDER.