Denver at Seattle

Denver has a proven winning head coach, Sean Payton at the helm. Payton picked the signal caller he wanted with quarterback Bo Nix stepping in. Four of five starters return to the offensive line. New defensive coordinator Vance Joseph did wonders, with the Broncos leading the NFL with 15 fumble recoveries while ranking second on third down (33.17%). Seattle lost its proven coach in Pete Carroll and turn to rookie head coach Mike Macdonald. First-year offensive coordinator Ryan Grubb will be calling plays in the NFL for the first time. The defensive line looks strong, though there are questions at inside linebacker. The Seahawks are on a 0-4-2 ATS run as a favorite, so back the big dog with the outstanding head coach. Play Denver.