Arizona at San Francisco

Arizona has had three extra days to recover from its first loss of the season, 24-21, against Green Bay last Thursday night when Kyler Murray was intercepted in the final minutes to clinch the victory for the Packers. Murray is dealing with an ankle injury and was not practicing this week, but he expects to play in this game. Murray went 22 of 33 for 274 yards against the Packers. San Francisco had lost four in a row before beating Chicago, 33-22, on Sunday as Jimmy Garoppolo threw for 322 yards and ran for 2 TDs for the 49ers, who lost the first meeting this season, 17-10, as a six-point underdog on Oct. 10. The Cardinals are 6-1-1 ATS the last eight meetings and 11-5 ATS their past 16 games versus teams with losing records. San Francisco is 1-7 ATS its last eight home games and 2-6-1 ATS overall its last nine November games. Arizona is #4 in the league in yards allowed and #3 in scoring defense. Play the Cardinals.