Arizona at Los Angeles

Arizona coach Bruce Arians is an outstanding coach with his teams at 5-2 ATS in preseason. Three potential starters and important backups will get their first significant playing time of the preseason. Guard Jonathan Cooper (turf toe) and linebacker Kevin Minter (pectoral muscle) will play and the team is hopeful that cornerback Tyrann Mathieu and nose tackle Alameda Ta'amu, who suffered knee injuries last December, make their preseason debuts. Cooper, Minter and Mathieu were expected to be starters this year, and Ta'amu split time a year ago with Dan Williams. The Arizona defense is deep, allowing 16.8 points per game. San Diego (1-2) had a weak defense last season and has not looked sharp, allowing 21 and 41 points the last two weeks. San Diego coach Mike McCoy admitted this week that they weren't going to show many things. This makes sense as Arizona and San Diego close out the preseason this week and then open the regular season 11 days later in Glendale, so the value is with the dog. Take Arizona.