Buffalo Bills vs Tennessee Titans

Combine the Bills (-455) and the Commanders (-385) into a 2-team parlay at -186 odds.

Well-coached Tennessee was the AFC's No. 1 seed last year but is a huge underdog. They also have an above-average QB in Ryan Tannehill (2 TDs, 0 INTs) and a balanced attack anchored by RB Derrick Henry. Henry had the best game of any back against the Bills' defense last year with 172 yards rushing (7.2 ypc) and 3 touchdowns in a 34-31 Titans win over Buffalo. NFL underdogs like the Titans that averaged 24+ points in the previous season are 44-21 ATS. Buffalo returns home from the West Coast after a Week 1 win at Los Angeles. The Buffalo offense wasn't in mid-season form turning it over 4 times and has a new offensive coordinator in Ken Dorsey after Brian Daboll left to run the Giants. They rebuilt the defensive line after a playoff loss to Kansas City letting go of six veterans. The defense will be without injured DTs Ed Oliver and Tim Settle tonight and the underdog is 10-1 ATS when these teams clash. Play Tennessee.

Tennessee will try to slow down the Buffalo offense by keeping it off the field as much as possible, as RB Derrick Henry continues to pile up yardage. Henry has rushed for 582 yards his last four games, including 130 against Jacksonville last week in Tennessee's 37-19 win. Ryan Tannehill went 14 of 22 for 197 yards and a touchdown against the Jaguars and Marcus Johnson caught three passes for 52 yards. Buffalo is 4-1, but three of the wins have been against Miami, Washington and Houston, who have a combined record of 4-14. The Titans won last year's meeting 42-16, even with Henry scoring two TDs, but gaining only 57 yards on 19 carries. The Titans are 7-2 ATS their past nine Monday games. Julio Jones returned to practice after missing two games with a hamstring injury. Tannehill hasn't thrown an interception his last two games despite being constantly pressured. Take the points with the Titans.