Buffalo Bills vs Jacksonville Jaguars

This will be Jacksonville's second consecutive game in London after defeating Atlanta 23-7 in Week 4 and bouncing back from a poor performance the week before when the Jaguars lost 37-17 to Houston. Trevor Lawrence threw for 207 yards on 23 of 30 with no interceptions and Darious Williams returned an interception 61 yards for a score for the Jaguars, who beat the Bills 9-6 in the last meeting in 2021. Jacksonville is 8-3 ATS its past 11 games, 6-0-1 ATS against teams with winning records and 3-0-1 ATS as an underdog of 3.5-10.0 points. Buffalo is just 1-4 ATS its past five games after totaling more than 350 yards its previous game and they are in letdown mode after their big game against Miami. Also, the Bills are 1-5 ATS their past six as favorites of more than three points versus a team coming off a double-digit win. Buffalo cornerback Tre'Davious White suffered an Achilles injury and is out for the year. The Dolphins did accumulate 393 yards of offense against the Bills on Sunday, but were stymied by lack of execution on third and fourth down conversions. Jacksonville has covered six of eight following a win and five of six as an underdog. Take the Jaguars.

Buffalo is a cold-weather team heading to the warm, humid Florida climate. They also have a division game on deck and are banged up on the offensive line. Guard Jon Feliciano (calf strain) is questionable along with left tackle Spencer Brown (back injury), who didn't play last week. This is their third road game in four contests, and they're a huge favorite. NFL road favorites that are outscoring opponents by 10+ on the season are 19-47 ATS after a win by 10+ points. Jacksonville prefers to run the football under first-year coach Urban Meyer, and the team gets No. 1 RB James Robinson back after he missed most of last week's game. Jacksonville is playing hard for this coaching staff, losing 24-21 at Cincinnati as a +7 dog, losing two home games by 10 and 12 points, along with an upset of Miami, 23-20. With the Bills 15-29 ATS off an AFC East win by 10+ points, plus 15-31 ATS off a home win against a division rival, back the huge home dog. Play Jacksonville.

Here's a game even Jacksonville can't blow. The Jaguars dominated the Steelers for 3+ quarters last week, then collapsed again. But this team is loaded with talent on defense, one of the most dominating units in the NFL. Jacksonville is fourth in yards allowed, third against the pass, and ninth in points surrendered (21.9 pg). The Jaguars are 8-2-2 ATS after allowing 250+ yards passing in their previous game. They won't allow that to this one-dimensional and truly awful Buffalo offense, ranking #31 in yards, and last in passing and points (13.7 pg). And the defense is #19 in points allowed (25.1 pg). Buffalo has been outscored by -114 points, most in the league. Five quarterbacks have combined for five TDs to 16 picks! The Bills are 10-21 ATS after allowing fewer than 15 points in their previous game. It's hard to remember that Buffalo made the playoffs last season, losing 10-3 to this Jaguars team when the Bills actually had a semi-respectable QB (Tyrod Taylor). But an offseason fire sale has made them the NFL laughingstock of 2018 and the visitors will easily break their skid. Play Jacksonville.

The surprising matchup between Buffalo and Jacksonville features two mediocre quarterbacks in Tyrod Taylor and Blake Bortles. The Jaguars lost to Tennessee last week 15-10 and it went UNDER by 15 points and Bortles completed only 44.1 percent of his passes with no touchdowns and two interceptions. He was also sacked twice and the Jaguars had only 229 total offense yards. Bortles has thrown 21 touchdown passes and 13 interceptions while managing not to cause too much trouble as in past seasons. Taylor did have a good game against Miami completing 19-of-27 for 204 yards and a touchdown. Running back LeSean McCoy, who has rushed for 1,586 yards, is questionable with an ankle injury. The Bills have gone UNDER four of their last six games and Jacksonville is 5-0 UNDER after an ATS loss. The Jaguars have stayed UNDER seven of their last games against AFC teams and four in a row after a straight-up loss. The Jags are second in the NFL in yards allowed while giving up just 16.8 points per game. Buffalo is #29 offensively and scoring only 18.9 points per game. Take the UNDER.