Note: These are computer-derived picks and do NOT represent my official
picks. In order to make final picks, there is much more analysis required
(injuries, trends, situations and other technical analysis). If you want
my full analysis, detailed write-ups and official picks be sure to
@
Indianapolis Colts
#455
Buffalo Bills
#456
November 21, 2021 1:00 PM ET
lines and odds
ATS
+7 (-115)
-7 (-105)
Moneyline
+251
-302
Total
OVER 49.5 (-110)
UNDER 49.5 (-110)
Public consensus
ATS
1063 (57%)
791 (43%)
Total
Over 562 (48%)
Under 603 (52%)
Computer Predictions
Predicted score
21.134
28.066
% Chance to win
26%
74%
ATS prediction
Moneyline prediction
Total prediction
UNDER 50
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