San Francisco at Detroit

San Francisco has a losing record and is a long way from home on a 2-4 skid, all at home. The offense is 17th in runs scored, while the pitching is 20th in ERA, and the defense has made the second-most errors. The Giants are 38-48 after a loss and starter Sean Manaea (4.50 ERA) is on a 4-12 run on the road. Manea had an ERA of 6.16 on the road last season in 83 innings and his ERA is over 10 away from home in the new campaign. Detroit comes home from a 3-1 win at Toronto as a +225 dog. Starter Joey Wentz looks to bounce back after a bad start against Boston after throwing well in the opener against unbeaten Tampa Bay. Last season, Wentz had a 3.03 with the Tigers while holding batters to a .195 average. The wagering value is on the home team to win the game or lose by one run. Play Detroit on the Run-Line.