Pittsburgh at Cincinnati

Pittsburgh hits the road for the first time this season. Pirates' lefty Francisco Liriano got the win opening day, but he is still 7-18 with a 5.29 ERA in 39 April appearances. The Pirates are also 4-9 when Liriano starts against the Reds. Cincinnati is home for the fourth straight game after sweeping Philadelphia by a 19-10 count. Jay Bruce did most of the damage with two home runs and a career high-tying five RBIs in Thursday's 10-6 victory. Cincinnati is 11-3 when pitcher Alfredo Simon faces the National League Central as a starter. The Reds won the 2015 season series 11-8 despite finishing 34 games behind the Pirates, so grab the home dog and play on Cincinnati.