Pittsburgh at Boston

Pittsburgh got its second win of the season as it defeated the Red Sox 7-6 on Monday when Bryan Reynolds hit a pair of solo home runs and the Pirates survived a five-run first inning by Boston. Roansy Contreras will make his first start of 2022 after finishing 5-5 with a 3.79 ERA and 1.27 WHIP for Pittsburgh last season. Nick Pivetta had a terrible April in 2022 as he was 0-3 with a 8.27 ERA and .297 opponent batting average and he finished the season 10-12 with a 4.56 ERA. The Red Sox have allowed 30 runs their first four games and it will be difficult for the offense to keep up with it. Boston has lost five of its past six interleague home games. Take the Pirates on the run line.