Philadelphia at Houston

Philadelphia stole a wild Game 1, 6-5, in 10 innings. Five relief pitchers got the job down, though three of them threw 20+ pitched. That's a concern for game Game 2 as the Phillies were ranked 18th in pitching ERA during an 87-75 regular season campaign. Zack Wheeler will start, with an ERA o 1.85 at home but 3.84 on the road. The Phillies are 8-20 in interleague road games, plus 17-35 in interleague road games against winning teams. Houston had the most wins in the AL during the regular season (106) and the second-most in all of baseball. Their pitching depth is outstanding, second in the majors in team ERA (2.90) with the second-most saves (53). The Astros are 16-4 in the last 20 starts made by Framber Valdez, who has a 1.42 ERA this postseason. Houston is 100-44 as a favorite, as well as 42-17 when the money line is -100 to -150. And road teams like the Phillies with a slugging percentage of .480 or higher over their last five October contests are 11-34. Play Houston.