Oakland at Philadelphia

Oakland has a weak offense at #21 in runs scored and loses the DH for this series. It's the end of a six-game trip after playing at Boston, 3,000 miles from home. Oakland is the first AL team to lose 50 road games and is on a 20-48 run away from home. Athletics lefty Sean Manaea was lit up at Fenway Park on Tuesday, allowing seven runs on 11 hits in 3+ innings of an 11-1 loss. He is 6-13 with a 5.03 ERA in 25 career road starts. Philadelphia is home for the sixth straight game, winning five of the last seven. The Phillies go with Henderson Alvarez, who had a 3.80 ERA over five seasons with Toronto and Miami, and makes his debut with his new team here. The Phillies have won six in a row against southpaws, making this a great situational spot for the home dog. Play Philadelphia.