Miami at San Francisco

San Francisco won an incredible 107 games in 2021 despite being picked to finish around .500, and although they won't have Buster Posey and Kevin Gausman this year, they still expect to contend again. Logan Webb gets the start in the opener, and he comes off of an 11-3 season with a 3.03 ERA, and he was nearly untouchable at home where he went 6-0 with a 1.96 ERA and .213 opponent batting average. Webb faced the Marlins once in 2021 and shut them out on three hits in seven innings. Miami continues to rebuild, but even after five years, they won only 67 games in 2021, and the lineup doesn't scare anyone. Sandy Alcantara went 9-15 last season and had a 4.01 ERA on the road compared to 2.41 at home. Alcantara faced the Giants twice last year and gave up six runs on 10 hits in 11 innings. Miami is 13-41 in its past 54 road games, and the Giants are 43-17 as home favorites. Play the Giants.