Colorado at Detroit

You have to really look hard at this one and toss out anything that may apply, because this is one of the strongest matchup trends in interleague play. The Tigers are the kings of interleague play - having absolutely dominated. After their win last night over the Rockies, they bring a 43-12 mark in their last 65 interleague games to this one. The Rockies have been average in interleague play as a whole, but when you separate that whole into home and away, there is a staggering difference. The Rockies have used their novel home park to frustrate their visitors from the AL to the tune of a 36-15 mark, but how the road tells a completely different tale. The Rockies on the road in interleague play have stumbled to a 15-31 mark, for -20.86 units. The Tigers are hot right now as well and there is only one way to go here, Tigers all the way.