Cincinnati at Chicago

Chicago is playing best at home (9-5), and the Reds are in town with a losing road mark. This is the end of a 10-game road trip for Cincinnati. The Reds are 9-32 as a road underdog, plus a miserable 5-21 in interleague games as an underdog. Chicago improved to 3-2 on its six-game homestand with an 8-2 win last night as Adam Eaton was the only member of the lineup without a hit. The White Sox are attempting to win their second straight series after taking two of three from Detroit during the week. Chicago is 6-2 as home chalk, and the White Sox are 41-19 in interleague games as a favorite. Cincinnati is also 2-12 against the White Sox, including 1-4 in this park. Play the White Sox.