Chicago at St. Louis

St. Louis has won three of four after defeating the Cubs 2-1 on Saturday when Yadier Molina broke a 1-1 tie with a home run leading off the seventh. Adam Wainwright has done his best work at home where he has a 3.00 ERA and a .228 opponent batting average, compared to 8.56 and .333 on the road. Wainwright faced the Cubs once in 2020 and gave up two runs in 6 1/3 innings, and Chicago hitters are batting .208 with a .336 slugging percentage against him in 188 at-bats. Zach Davies gave up three runs on seven hits in five innings against Washington on Tuesday, but he has been terrible on the road where he has allowed 14 earned runs on 21 hits in 14 2/3 innings. The Cardinals are 13-4 after scoring two or fewer runs their previous game, and they have won six of their past seven home games. The Cubs have lost 13 of their past 19 road games. Take the Cardinals.