Boston at Baltimore

The Boston Red Sox won it all a year ago, and while the pitching depth may be called into question, the top of the rotation is as good as any, led by Jon Lester. Lester has a big plus as he has completely neutralized the O's best hitter and slugger Chris Davis, who is just 3-24 against him. The Orioles lack pitching, and that can be seen in the fact that Chris Tillman gets the ball on Opening Day, who had a 16-7 record in 2013, but just a 3.71 ERA. Boston has been a proven commodity on the road as a favorite where they are 35-17 in their last 52. Tillman closed last year with the O's at just 3-7, and his last five starts as a home dog have been a disappointing 1-4. Make the play on Boston.