Wake Forest at Louisville

Bobby Petrino knew it would be tough replacing QB Lamar Jackson, who basically was the Louisville offense. He also lost seven starters on defense, so both sides have suffered tremendous losses. Louisville has thus fallen hard at 2-5 on the season. The offense is down 18 points per game and the defense is surrendering an additional TD per contest, so a combined 25 point drop off. Wake has four losses, but to Clemson, Notre Dame, Florida State, and Boston College; and Louisville are not close to the caliber of any of them. Wake is 3-4, which holds this line down, but they have been better than their subpar opponents on the season. Play on Wake Forest.