USC is 5-2 in the Pac-12 and leads the conference in scoring. In fact, the Trojans are No. 1 in the nation in scoring (45.5 points per game) behind reigning Heisman Trophy-winning QB Caleb Williams (28 TDs, 4 INTs). The offense is also seventh in yards (485.5 per game) and third in passing (326.7). Oregon's pass defense is 50th in the country. You have to wonder how the Ducks will handle the late-season pressure to finish strong. They failed that test last year, starting 8-1, but then losing to Washington (37-24) in November as a 12-point favorite along with a loss to Oregon State (38-34). They finished 2022 going 2-2, including a narrow 28-27 bowl win over North Carolina as a 13-point favorite getting a TD in the final seconds. An upset by the No. 1 scoring offense in the country wouldn't be a shock. Back USC on the moneyline.
TAKE THE GUESSWORK OUT OF SPORTS BETTING
Get my free CFB picks and predictions.
Join 412,084 Subscribers!