Notre Dame at Louisville

Notre Dame has to feel stunned after they had Ohio St. on the brink in their contest two weeks ago vs. Ohio St. only to lose on the final play. They could once again be playing without their top 2 WRs and the sting from the last game could certainly come into play here vs. a competent Louisville team that has started the season at 5-0. This will be the third straight game for Notre Dame where the opponent comes into the game unbeaten. The Irish have been in two straight games where they have had to emotionally be ready to go full throttle, and might not be up to task against a Louisville team that is going to be confident, and rocking at home. The Irish also may have one eye on their next game, vs. another unbeaten team in USC. Tough spot for Notre Dame. I like Louisville.