The teams are meeting for the first time since 2015 when Iowa won 35-27 as a seven-point favorite. The Hawkeyes are off to a good start this season with a 4-1 record both straight up and ATS following their impressive 48-31 win at Minnesota last week. Nate Stanley finished 23-of-39 for 314 yards and four touchdowns and Ihmir Smith-Marsette led the receiving corps with 78 yards on three catches. Iowa's defense is #4 in the country in yards allowed (272.4 per game) and #5 in rushing defense (84.4 yards per game). Indiana has a 4-2 record, but just 2-4 ATS and has played a weak schedule except for Ohio State and Michigan State and the Hoosiers lost those games by an average of 18.5 points. The Buckeyes racked up 609 total yards of offense against the Hoosiers defense last week, including 455 passing yards. Indiana is 0-6 ATS its last six games after a loss and 1-6 its last seven following an ATS win. Also, the Hoosiers are 3-12-1 ATS their last 16 conference games and 3-7-1 ATS their last 11 home contests. Meanwhile, Iowa has covered 20 of its last 29 road games and six of its last seven games overall dating to last season. The favorite has covered the number five of the last seven meetings. Play Iowa.
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