Indiana at Ohio State

This would not have been expected to be a conference marquee matchup before the season started, but that is what it has turned out to be as the two undefeated teams battle in Columbus. However, Ohio State has been overpowering its opponents while averaging 46.3 points and 511.3 total offense yards per game. Justin Fields has thrown for 908 yards and 11 touchdowns with an astounding 86.7 completion rate and no interceptions. The Buckeyes game was cancelled last week after they beat Rutgers 49-27 in a game that wasn't as close as the score indicates. A closer look at the Hoosiers' schedule shows their opponents have a combined record of 3-13. Indiana quarterback Michael Penix Jr. completed 25 of 38 for 320 yards and two TDs and two interceptions against Michigan State and he'll be facing a tougher defense in this matchup. The Hoosiers are 2-10-1 ATS their last 13 games after winning by at least 20 points and Ohio State has covered 11 of its last 14 after winning by 20 points or more. Also, the Buckeyes are 14-6 ATS their last 20 games overall and 11-4 ATS in conference games. Take Ohio State.