Clemson at Syracuse

Clemson won last year's meeting, 47-21, but this is a different team that hasn't scored more than 21 points in four of its five games this season. The Tigers got by Boston College, 19-13, but they didn't cover as a 14.5-point favorite, and DJ Uiagalelei went only 13 of 28 for 207 yards and no touchdowns. Kobe Pace ran for 125 yards on 19 carries, including a 59-yard TD run for the Tigers. Syracuse suffered a tough overtime loss to Wake Forest after tying the game with a 28-yard TD pass to Sean Tucker with 21 seconds left in regulation. Garrett Shrader completed 15 of 27 for 160 yards and 2 TDs with no interceptions. He also ran for 178 yards on 29 carries with a touchdown. Syracuse actually prefers to get the running game going with Shrader and then take advantage of a bewildered opposing defense on passing downs. Clemson is 0-6 ATS its last six games, and the underdog is 5-2 ATS the past seven meetings. Syracuse has covered five of its last six home games and six of seven overall as a dog. Play Syracuse.