Virginia Tech vs. Louisville

Coach Chris Mack lost all his starters from last season, but there were enough players with experience to make it a smoother transaction than expected. The Cardinals have responded with a 7-1 record, including a big win over Kentucky. The Cardinals defeated Boston College on Saturday 76-64, while holding the Eagles to 33.3-percent shooting, and the Louisville defense is allowing opponents just a .386 field goal percentage on the season. David Johnson led the Cardinals with 20 points and eight rebounds against Boston College, and Carlik Jones added 15 points and nine boards. Louisville has won and covered the last four meetings and Virginia Tech is 1-7 ATS its last eight games as an underdog, and 7-17 ATS its last 24 games overall. The Cardinals are 6-2-1 ATS their last nine home contests. Take Louisville.