Michigan State vs. Louisville

Michigan State is playing its best defense at the right time allowing 63, 54, and 58 points the last three games. That's why Tom Izzo's teams have been to the Sweet 16 for the seveth time in eight years. Michigan State has great balance on offense and is fourth in the country in assists while shooting 47.1% as a team (32nd). The Spartans have held opponents to a 39.4 field-goal percentage this season, 33.1 percent in three tournament games. Michigan State is 24-4 when giving up less than 70 points. Michigan State is on a 10-4 ATS run and 4-0 ATS in non-conference games. Louisville has been in transition since midseason, dismissing senior point guard Chris Jones, and replacing him with true freshman Quentin Snider. The Cardinals are 1-5-1 ATS in their last seven non-conference games. Play Michigan State.