Loyola, Chicago brought back a lot of experience from a year ago and think they can challenge and knock off Butler atop the Horizon. They have gotten off to a great start at 6-0, with five players averaging in double-figures. They have their top eight players all shooting 46% or higher from the field and are tough to defend and deep. San Francisco was whipped by 17 points in their last outing vs Montana St. and will be hard pressed to stay with Loyola. The homecourt hasn't been so kind to the Dons as, despite their 2-0 mark on home hardwood so far this season, they are 11-26 ATS defending their court as a home dog. I'll go with Loyola in this one.
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